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Detrimental effect of post Status Epilepticus treatment with ROCK inhibitor Y-27632 in a pilocarpine model of temporal lobe epilepsy

Temporal lobe epilepsy (TLE) is the most common type of epilepsy in adults where 20–30% of the patients are refractory to currently available anti-epileptic drugs. The RhoA/Rho-kinase signaling pathway activation has been involved in inflammatory responses, neurite outgrowth and neuronal death under...

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Detalles Bibliográficos
Autores principales: Kourdougli, Nazim, Varpula, Saara, Chazal, Genevieve, Rivera, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615811/
https://www.ncbi.nlm.nih.gov/pubmed/26557054
http://dx.doi.org/10.3389/fncel.2015.00413