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DNA double strand break repair pathway choice: a chromatin based decision?

DNA double-strand breaks (DSBs) are highly toxic lesions that can be rapidly repaired by 2 main pathways, namely Homologous Recombination (HR) and Non Homologous End Joining (NHEJ). The choice between these pathways is a critical, yet not completely understood, aspect of DSB repair. We recently foun...

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Detalles Bibliográficos
Autores principales: Clouaire, T, Legube, G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615830/
https://www.ncbi.nlm.nih.gov/pubmed/25675367
http://dx.doi.org/10.1080/19491034.2015.1010946