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The distinct functions of CENP-C and CENP-T/W in centromere propagation and function in Xenopus egg extracts

The centromere is the chromosomal region in which the kinetochore is assembled to orchestrate chromosome segregation. It is defined by the presence of a histone H3 variant called Centromere Protein A (CENP-A) or CenH3. Propagation of centromere identity entails deposition of new CENP-A upon exit fro...

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Detalles Bibliográficos
Autores principales: Krizaic, Iva, Williams, Samantha J, Sánchez, Patricia, Rodríguez-Corsino, Miriam, Stukenberg, P Todd, Losada, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615894/
https://www.ncbi.nlm.nih.gov/pubmed/25569378
http://dx.doi.org/10.1080/19491034.2014.1003509