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Flow-cytometric visualization of C>U mRNA editing reveals the dynamics of the process in live cells
APOBEC1 is the catalytic subunit of the complex that edits ApolipoproteinB (ApoB) mRNA, which specifically deaminates cytidine 6666 to uracil in the human transcript. The editing leads to the generation of a stop codon, resulting in the synthesis of a truncated form of ApoB. We have developed a meth...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Taylor & Francis
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615904/ https://www.ncbi.nlm.nih.gov/pubmed/25806564 http://dx.doi.org/10.1080/15476286.2015.1026033 |