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The human complement inhibitor Sushi Domain-Containing Protein 4 (SUSD4) expression in tumor cells and infiltrating T cells is associated with better prognosis of breast cancer patients

BACKGROUND: The human Sushi Domain-Containing Protein 4 (SUSD4) was recently shown to function as a novel inhibitor of the complement system, but its role in tumor progression is unknown. METHODS: Using immunohistochemistry and quantitative PCR, we investigated SUSD4 expression in breast cancer tiss...

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Detalles Bibliográficos
Autores principales: Englund, Emelie, Reitsma, Bart, King, Ben C., Escudero-Esparza, Astrid, Owen, Sioned, Orimo, Akira, Okroj, Marcin, Anagnostaki, Lola, Jiang, Wen G., Jirström, Karin, Blom, Anna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615997/
https://www.ncbi.nlm.nih.gov/pubmed/26480818
http://dx.doi.org/10.1186/s12885-015-1734-7