Overshoot during phenotypic switching of cancer cell populations

The dynamics of tumor cell populations is hotly debated: do populations derive hierarchically from a subpopulation of cancer stem cells (CSCs), or are stochastic transitions that mutate differentiated cancer cells to CSCs important? Here we argue that regulation must also be important. We sort human...

Descripción completa

Detalles Bibliográficos
Autores principales: Sellerio, Alessandro L., Ciusani, Emilio, Ben-Moshe, Noa Bossel, Coco, Stefania, Piccinini, Andrea, Myers, Christopher R., Sethna, James P., Giampietro, Costanza, Zapperi, Stefano, La Porta, Caterina A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616026/
https://www.ncbi.nlm.nih.gov/pubmed/26494317
http://dx.doi.org/10.1038/srep15464

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616026/
https://www.ncbi.nlm.nih.gov/pubmed/26494317
http://dx.doi.org/10.1038/srep15464

Ejemplares similares