Lactate dehydrogenase-A inhibition induces human glioblastoma multiforme stem cell differentiation and death

Therapies that target the signal transduction and metabolic pathways of cancer stem cells (CSCs) are innovative strategies to effectively reduce the recurrence and significantly improve the outcome of glioblastoma multiforme (GBM). CSCs exhibit an increased rate of glycolysis, thus rendering them in...

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Detalles Bibliográficos
Autores principales: Daniele, Simona, Giacomelli, Chiara, Zappelli, Elisa, Granchi, Carlotta, Trincavelli, Maria Letizia, Minutolo, Filippo, Martini, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616042/
https://www.ncbi.nlm.nih.gov/pubmed/26494310
http://dx.doi.org/10.1038/srep15556

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616042/
https://www.ncbi.nlm.nih.gov/pubmed/26494310
http://dx.doi.org/10.1038/srep15556

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