Sclerostin Antibody Treatment Increases Bone Formation, Bone Mass, and Bone Strength of Intact Bones in Adult Male Rats

We investigated the systemic effect of sclerostin monoclonal antibody (Scl-Ab) treatment on intact non-operated bones in an open osteotomy male Sprague Dawley (SD) rat model. Six-month-old male SD rats were subjected to transverse osteotomy at the right femur mid-shaft. Rats were injected subcutaneo...

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Detalles Bibliográficos
Autores principales: Suen, Pui Kit, Zhu, Tracy Y., Chow, Dick Ho Kiu, Huang, Le, Zheng, Li-Zhen, Qin, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616053/
https://www.ncbi.nlm.nih.gov/pubmed/26494536
http://dx.doi.org/10.1038/srep15632

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616053/
https://www.ncbi.nlm.nih.gov/pubmed/26494536
http://dx.doi.org/10.1038/srep15632

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