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Sclerostin Antibody Treatment Increases Bone Formation, Bone Mass, and Bone Strength of Intact Bones in Adult Male Rats

We investigated the systemic effect of sclerostin monoclonal antibody (Scl-Ab) treatment on intact non-operated bones in an open osteotomy male Sprague Dawley (SD) rat model. Six-month-old male SD rats were subjected to transverse osteotomy at the right femur mid-shaft. Rats were injected subcutaneo...

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Detalles Bibliográficos
Autores principales:	Suen, Pui Kit, Zhu, Tracy Y., Chow, Dick Ho Kiu, Huang, Le, Zheng, Li-Zhen, Qin, Ling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616053/ https://www.ncbi.nlm.nih.gov/pubmed/26494536 http://dx.doi.org/10.1038/srep15632

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