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Testicular expression of the Lin28/let-7 system: Hormonal regulation and changes during postnatal maturation and after manipulations of puberty

The Lin28/let-7 system, which includes the RNA-binding proteins, Lin28a/Lin28b, and let-7 miRNAs, has emerged as putative regulator of puberty and male gametogenesis; yet, its expression pattern and regulation in postnatal testis remain ill defined. We report herein expression profiles of Lin28 and...

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Detalles Bibliográficos
Autores principales: Sangiao-Alvarellos, S., Manfredi-Lozano, M., Ruiz-Pino, F., León, S., Morales, C., Cordido, F., Gaytán, F., Pinilla, L., Tena-Sempere, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616161/
https://www.ncbi.nlm.nih.gov/pubmed/26494358
http://dx.doi.org/10.1038/srep15683