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Downregulated miR-45 Inhibits the G1-S Phase Transition by Targeting Bmi-1 in Breast Cancer

Bmi-1 (B cell-specific Moloney murine leukemia virus integration site 1) is upregulated in breast cancer and was involved in many malignant progressions of breast cells, including cell proliferation, stem cell pluripotency, and cancer initiation. However, the epigenetic regulatory mechanism of Bmi-1...

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Detalles Bibliográficos
Autores principales: Wang, Lan, Liu, Jun-Ling, Yu, Liang, Liu, Xiang-Xia, Wu, Hong-Mei, Lei, Fang-Yong, Wu, Shu, Wang, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616407/
https://www.ncbi.nlm.nih.gov/pubmed/26020378
http://dx.doi.org/10.1097/MD.0000000000000718