BIM Gene Polymorphism Lowers the Efficacy of EGFR-TKIs in Advanced Nonsmall Cell Lung Cancer With Sensitive EGFR Mutations: A Systematic Review and Meta-Analysis

The strong association between bcl-2-like 11 (BIM) triggered apoptosis and the presence of epidermal growth factor receptor (EGFR) mutations has been proven in nonsmall cell lung cancer (NSCLC). However, the relationship between EGFR-tyrosine kinase inhibitor's (TKI's) efficacy and BIM pol...

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Detalles Bibliográficos
Autores principales: Huang, Wu Feng, Liu, Ai Hua, Zhao, Hai Jin, Dong, Hang Ming, Liu, Lai Yu, Cai, Shao Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2015
Materias:
5700
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616439/
https://www.ncbi.nlm.nih.gov/pubmed/26287412
http://dx.doi.org/10.1097/MD.0000000000001263

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616439/
https://www.ncbi.nlm.nih.gov/pubmed/26287412
http://dx.doi.org/10.1097/MD.0000000000001263

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