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KRAS Mutation Status Is Not a Predictor for Tumor Response and Survival in Rectal Cancer Patients Who Received Preoperative Radiotherapy With 5-Fluoropyrimidine Followed by Curative Surgery

We evaluated the tumor response and survival according to the KRAS oncogene status in locally advanced rectal cancer. One hundred patients with locally advanced rectal cancer (cT3-4N0-2M0) received preoperative radiation of 50.4 Gy in 28 fractions with 5-fluorouracil and total mesorectal excision. T...

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Detalles Bibliográficos
Autores principales: Lee, Jeong Won, Lee, Jong Hoon, Shim, Byoung Yong, Kim, Sung Hwan, Chung, Mi-Joo, Kye, Bong-Hyeon, Kim, Hyung Jin, Cho, Hyeon Min, Jang, Hong Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616597/
https://www.ncbi.nlm.nih.gov/pubmed/26252300
http://dx.doi.org/10.1097/MD.0000000000001284