A Functional Polymorphism in the Promoter of MiR-143/145 Is Associated With the Risk of Cervical Squamous Cell Carcinoma in Chinese Women: A Case–Control Study

MiR-143/145 is down-regulated in cervical cancer, which may serve as a tumor suppressor by targeting KRAS and Ras-responsive element-binding protein (RREB1). Activated KRAS leads to down-regulation of miR-143/145 transcription in a RREB1-dependent manner, establishing a miR-143/145-KRAS-RREB1 feedba...

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Detalles Bibliográficos
Autores principales: Liang, Yundan, Sun, Ruifen, Li, Lijuan, Yuan, Fang, Liang, Weibo, Wang, Li, Nie, Xinwen, Chen, Peng, Zhang, Lin, Gao, Linbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2015
Materias:
4400
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616598/
https://www.ncbi.nlm.nih.gov/pubmed/26252302
http://dx.doi.org/10.1097/MD.0000000000001289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616598/
https://www.ncbi.nlm.nih.gov/pubmed/26252302
http://dx.doi.org/10.1097/MD.0000000000001289

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