A Pan-Cancer Catalogue of Cancer Driver Protein Interaction Interfaces

Despite their importance in maintaining the integrity of all cellular pathways, the role of mutations on protein-protein interaction (PPI) interfaces as cancer drivers has not been systematically studied. Here we analyzed the mutation patterns of the PPI interfaces from 10,028 proteins in a pan-canc...

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Detalles Bibliográficos
Autores principales: Porta-Pardo, Eduard, Garcia-Alonso, Luz, Hrabe, Thomas, Dopazo, Joaquin, Godzik, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616621/
https://www.ncbi.nlm.nih.gov/pubmed/26485003
http://dx.doi.org/10.1371/journal.pcbi.1004518

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616621/
https://www.ncbi.nlm.nih.gov/pubmed/26485003
http://dx.doi.org/10.1371/journal.pcbi.1004518

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