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A Pan-Cancer Catalogue of Cancer Driver Protein Interaction Interfaces
Despite their importance in maintaining the integrity of all cellular pathways, the role of mutations on protein-protein interaction (PPI) interfaces as cancer drivers has not been systematically studied. Here we analyzed the mutation patterns of the PPI interfaces from 10,028 proteins in a pan-canc...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616621/ https://www.ncbi.nlm.nih.gov/pubmed/26485003 http://dx.doi.org/10.1371/journal.pcbi.1004518 |