Epigenetic Modifications in the Biology of Nonalcoholic Fatty Liver Disease: The Role of DNA Hydroxymethylation and TET Proteins

The 5-Hydroxymethylcytosine (5-hmC) is an epigenetic modification whose role in the pathogenesis of metabolic-related complex diseases remains unexplored; 5-hmC appears to be prevalent in the mitochondrial genome. The Ten-Eleven-Translocation (TET) family of proteins is responsible for catalyzing th...

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Detalles Bibliográficos
Autores principales: Pirola, Carlos J., Scian, Romina, Gianotti, Tomas Fernández, Dopazo, Hernán, Rohr, Cristian, Martino, Julio San, Castaño, Gustavo O., Sookoian, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2015
Materias:
4500
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616643/
https://www.ncbi.nlm.nih.gov/pubmed/26356709
http://dx.doi.org/10.1097/MD.0000000000001480

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616643/
https://www.ncbi.nlm.nih.gov/pubmed/26356709
http://dx.doi.org/10.1097/MD.0000000000001480

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