Cargando…

Epigenetic Modifications in the Biology of Nonalcoholic Fatty Liver Disease: The Role of DNA Hydroxymethylation and TET Proteins

The 5-Hydroxymethylcytosine (5-hmC) is an epigenetic modification whose role in the pathogenesis of metabolic-related complex diseases remains unexplored; 5-hmC appears to be prevalent in the mitochondrial genome. The Ten-Eleven-Translocation (TET) family of proteins is responsible for catalyzing th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pirola, Carlos J., Scian, Romina, Gianotti, Tomas Fernández, Dopazo, Hernán, Rohr, Cristian, Martino, Julio San, Castaño, Gustavo O., Sookoian, Silvia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer Health 2015
Materias:	4500
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616643/ https://www.ncbi.nlm.nih.gov/pubmed/26356709 http://dx.doi.org/10.1097/MD.0000000000001480

Ejemplares similares

Heat Shock Protein 27 is down-regulated in Ballooned Hepatocytes of Patients with Nonalcoholic Steatohepatitis (NASH)
por: Sookoian, Silvia, et al.
Publicado: (2016)

Genetic variation in long noncoding RNAs and the risk of nonalcoholic fatty liver disease
por: Sookoian, Silvia, et al.
Publicado: (2017)

A Rare Nonsense Mutation in the Glucokinase Regulator Gene Is Associated With a Rapidly Progressive Clinical Form of Nonalcoholic Steatohepatitis
por: Pirola, Carlos J., et al.
Publicado: (2018)

Metastasis‐associated lung adenocarcinoma transcript 1 as a common molecular driver in the pathogenesis of nonalcoholic steatohepatitis and chronic immune‐mediated liver damage
por: Sookoian, Silvia, et al.
Publicado: (2018)

Lack of evidence supporting a role of TMC4-rs641738 missense variant—MBOAT7- intergenic downstream variant—in the Susceptibility to Nonalcoholic Fatty Liver Disease
por: Sookoian, Silvia, et al.
Publicado: (2018)

Repurposing drugs to target nonalcoholic steatohepatitis
por: Sookoian, Silvia, et al.
Publicado: (2019)

Genetic predisposition in nonalcoholic fatty liver disease
por: Sookoian, Silvia, et al.
Publicado: (2017)

Personalized medicine in nonalcoholic fatty liver disease
por: Pirola, Carlos J., et al.
Publicado: (2022)

Epigenetic regulation of intestinal stem cells by Tet1-mediated DNA hydroxymethylation
por: Kim, Rinho, et al.
Publicado: (2016)

The lipidome in nonalcoholic fatty liver disease: actionable targets
por: Pirola, Carlos J., et al.
Publicado: (2021)

Use of a Diabetes Self-Assessment Score to Predict Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis
por: Kim, Gyuri, et al.
Publicado: (2015)

Multiomics biomarkers for the prediction of nonalcoholic fatty liver disease severity
por: Pirola, Carlos J, et al.
Publicado: (2018)

Disease severity predicts higher healthcare costs among hospitalized nonalcoholic fatty liver disease/nonalcoholic steatohepatitis (NAFLD/NASH) patients in Spain
por: Romero-Gomez, Manuel, et al.
Publicado: (2020)

TET Upregulation Leads to 5-Hydroxymethylation Enrichment in Hepatoblastoma
por: Rivas, Maria Prates, et al.
Publicado: (2019)

Nonalcoholic Fatty Liver Disease for Identification of Preclinical Carotid Atherosclerosis
por: Sinn, Dong Hyun, et al.
Publicado: (2016)

Risk factors of nonalcoholic fatty liver disease in healthy women
por: Guan, Hui, et al.
Publicado: (2023)

Systems Biology Elucidates Common Pathogenic Mechanisms between Nonalcoholic and Alcoholic-Fatty Liver Disease
por: Sookoian, Silvia, et al.
Publicado: (2013)

Precision medicine in nonalcoholic fatty liver disease: New therapeutic insights from genetics and systems biology
por: Sookoian, Silvia, et al.
Publicado: (2020)

Nonalcoholic fatty liver was associated with asymptomatic gallstones in a Chinese population
por: Qiao, Qiao-Hua, et al.
Publicado: (2017)

Nonalcoholic steatohepatitis: A scientometric analysis of publications during 1980–2018
por: Trifan, Anca, et al.
Publicado: (2019)

Efficacy of probiotics on nonalcoholic fatty liver disease: A meta-analysis
por: Zhou, Xiangyu, et al.
Publicado: (2023)

Development of de novo nonalcoholic fatty liver disease following pancreatectomy
por: Patel, Vanisha, et al.
Publicado: (2023)

The metabolic influence of duodenal mucosal resurfacing for nonalcoholic fatty liver disease
por: Chuang, Te-Jung, et al.
Publicado: (2023)

Association of resting heart rate with nonalcoholic fatty liver disease in postmenopausal women
por: Kim, Hong-Bae, et al.
Publicado: (2020)

Thyroid-stimulating hormone is associated with nonalcoholic steatohepatitis in patients with chronic hepatitis B
por: Liu, Liang, et al.
Publicado: (2019)

A nomogram incorporated lifestyle indicators for predicting nonalcoholic fatty liver disease
por: Peng, Kaili, et al.
Publicado: (2021)

Clinical and sociodemographic determinants of disease progression in patients with nonalcoholic steatohepatitis in the United States
por: Ruiz-Casas, Leonardo, et al.
Publicado: (2021)

The Presence of White Matter Lesions Is Associated With the Fibrosis Severity of Nonalcoholic Fatty Liver Disease
por: Petta, Salvatore, et al.
Publicado: (2016)

Nonalcoholic Fatty Liver Disease: A Negative Risk Factor for Colorectal Cancer Prognosis
por: You, Jie, et al.
Publicado: (2015)

Components of metabolic syndrome increase the risk of mortality in nonalcoholic fatty liver disease (NAFLD)
por: Golabi, Pegah, et al.
Publicado: (2018)

Candidate genes investigation for severe nonalcoholic fatty liver disease based on bioinformatics analysis
por: Qi, Shan, et al.
Publicado: (2017)

Association between Helicobacter pylori infection and nonalcoholic fatty liver: A meta-analysis
por: Liu, Rongqiang, et al.
Publicado: (2019)

Reversal of nonalcoholic fatty liver disease reduces the risk of cardiovascular disease among Korean
por: Oh, Yun Hwan, et al.
Publicado: (2023)

Repurposing drugs to target nonalcoholic steatohepatitis: Auranofin, a gold-organic molecule complex for the treatment of a specifc complex trait
por: Pirola, Carlos J., et al.
Publicado: (2022)

The Profiles of Tet-Mediated DNA Hydroxymethylation in Human Gliomas
por: Brągiel-Pieczonka, Aneta, et al.
Publicado: (2022)

Validation of the Fatty Liver Index for Nonalcoholic Fatty Liver Disease in Middle-Aged and Elderly Chinese
por: Huang, Xiaolin, et al.
Publicado: (2015)

The expression of thymosin β4 in chronic hepatitis B combined nonalcoholic fatty liver disease
por: Liang, Jing, et al.
Publicado: (2016)

Nonalcoholic Cirrhosis Increased Risk of Digestive Tract Malignancies: A Population-Based Cohort Study
por: Sun, Li-Min, et al.
Publicado: (2015)

Cost-effectiveness analysis of ultrasonography screening for nonalcoholic fatty liver disease in metabolic syndrome patients
por: Phisalprapa, Pochamana, et al.
Publicado: (2017)

Comparison of noninvasive scoring systems for the prediction of nonalcoholic fatty liver disease in metabolic syndrome patients
por: Saokaew, Surasak, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_0oc5te5sl78i2ir1tvveh737hs