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The Non-Obese Diabetic Mouse Strain as a Model to Study CD8(+) T Cell Function in Relapsing and Progressive Multiple Sclerosis

Multiple sclerosis (MS) is a neurodegenerative disease resulting from an autoimmune attack on central nervous system (CNS) myelin. Although CD4(+) T cell function in MS pathology has been extensively studied, there is also strong evidence that CD8(+) T lymphocytes play a key role. Intriguingly, CD8(...

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Detalles Bibliográficos
Autores principales: Ignatius Arokia Doss, Prenitha Mercy, Roy, Andrée-Pascale, Wang, AiLi, Anderson, Ana Carrizosa, Rangachari, Manu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617102/
https://www.ncbi.nlm.nih.gov/pubmed/26557120
http://dx.doi.org/10.3389/fimmu.2015.00541