Thyroid hormone reduces PCSK9 and stimulates bile acid synthesis in humans

Reduced plasma LDL-cholesterol is a hallmark of hyperthyroidism and is caused by transcriptional stimulation of LDL receptors in the liver. Here, we investigated whether thyroid hormone (TH) actions involve other mechanisms that may also account for the reduction in LDL-cholesterol, including effect...

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Detalles Bibliográficos
Autores principales: Bonde, Ylva, Breuer, Olof, Lütjohann, Dieter, Sjöberg, Stefan, Angelin, Bo, Rudling, Mats
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2014
Materias:
Patient-Oriented and Epidemiological Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617142/
https://www.ncbi.nlm.nih.gov/pubmed/25172631
http://dx.doi.org/10.1194/jlr.M051664

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617142/
https://www.ncbi.nlm.nih.gov/pubmed/25172631
http://dx.doi.org/10.1194/jlr.M051664

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