Adiposity significantly modifies genetic risk for dyslipidemia

Recent genome-wide association studies have identified multiple loci robustly associated with plasma lipids, which also contribute to extreme lipid phenotypes. However, these common genetic variants explain <12% of variation in lipid traits. Adiposity is also an important determinant of plasma li...

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Detalles Bibliográficos
Autores principales: Cole, Christopher B., Nikpay, Majid, Lau, Paulina, Stewart, Alexandre F. R., Davies, Robert W., Wells, George A., Dent, Robert, McPherson, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2014
Materias:
Patient-Oriented and Epidemiological Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617143/
https://www.ncbi.nlm.nih.gov/pubmed/25225679
http://dx.doi.org/10.1194/jlr.P052522

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617143/
https://www.ncbi.nlm.nih.gov/pubmed/25225679
http://dx.doi.org/10.1194/jlr.P052522

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