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An integrative systems genetics approach reveals potential causal genes and pathways related to obesity

BACKGROUND: Obesity is a multi-factorial health problem in which genetic factors play an important role. Limited results have been obtained in single-gene studies using either genomic or transcriptomic data. RNA sequencing technology has shown its potential in gaining accurate knowledge about the tr...

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Detalles Bibliográficos
Autores principales: Kogelman, Lisette J. A., Zhernakova, Daria V., Westra, Harm-Jan, Cirera, Susanna, Fredholm, Merete, Franke, Lude, Kadarmideen, Haja N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617184/
https://www.ncbi.nlm.nih.gov/pubmed/26482556
http://dx.doi.org/10.1186/s13073-015-0229-0