An Orthologous Epigenetic Gene Expression Signature Derived from Differentiating Embryonic Stem Cells Identifies Regulators of Cardiogenesis

Here we used predictive gene expression signatures within a multi-species framework to identify the genes that underlie cardiac cell fate decisions in differentiating embryonic stem cells. We show that the overlapping orthologous mouse and human genes are the most accurate candidate cardiogenic gene...

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Detalles Bibliográficos
Autores principales: Busser, Brian W., Lin, Yongshun, Yang, Yanqin, Zhu, Jun, Chen, Guokai, Michelson, Alan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617299/
https://www.ncbi.nlm.nih.gov/pubmed/26485529
http://dx.doi.org/10.1371/journal.pone.0141066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617299/
https://www.ncbi.nlm.nih.gov/pubmed/26485529
http://dx.doi.org/10.1371/journal.pone.0141066

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