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Differential ability of MSCs isolated from placenta and cord as feeders for supporting ex vivo expansion of umbilical cord blood derived CD34(+) cells

INTRODUCTION: Ex vivo expansion of umbilical cord blood (UCB) is attempted to increase cell numbers to overcome the limitation of cell dose. Presently, suspension cultures or feeder mediated co-cultures are performed for expansion of hematopoietic stem cells (HSCs). Mesenchymal stem cells (MSCs) hav...

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Detalles Bibliográficos
Autores principales: Kadekar, Darshana, Kale, Vaijayanti, Limaye, Lalita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617445/
https://www.ncbi.nlm.nih.gov/pubmed/26481144
http://dx.doi.org/10.1186/s13287-015-0194-y