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Chemical tagging and customizing of cellular chromatin states using ultrafast trans-splicing inteins

Post-translational modification of the histone proteins in chromatin plays a central role in epigenetic control of DNA-templated processes in eukaryotic cells. Developing methods that enable the structure of histones to be manipulated is therefore essential to understand the biochemical mechanisms u...

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Detalles Bibliográficos
Autores principales: David, Yael, Vila-Perelló, Miquel, Verma, Shivam, Muir, Tom W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617616/
https://www.ncbi.nlm.nih.gov/pubmed/25901817
http://dx.doi.org/10.1038/nchem.2224