Single-Cell Analysis of RNA Virus Infection Identifies Multiple Genetically Diverse Viral Genomes within Single Infectious Units

Genetic diversity enables a virus to colonize novel hosts, evade immunity, and evolve drug resistance. However, viral diversity is typically assessed at the population level. Given the existence of cell-to-cell variation, it is critical to understand viral genetic structure at the single-cell level....

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Detalles Bibliográficos
Autores principales: Combe, Marine, Garijo, Raquel, Geller, Ron, Cuevas, José M., Sanjuán, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617633/
https://www.ncbi.nlm.nih.gov/pubmed/26468746
http://dx.doi.org/10.1016/j.chom.2015.09.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617633/
https://www.ncbi.nlm.nih.gov/pubmed/26468746
http://dx.doi.org/10.1016/j.chom.2015.09.009

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