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Peroxisomal Import Reduces the Proapoptotic Activity of Deubiquitinating Enzyme USP2
The human deubiquitinating enzyme ubiquitin-specific protease 2 (USP2) regulates multiple cellular pathways, including cell proliferation and apoptosis. As a result of alternative splicing four USP2 isoenzymes are expressed in human cells of which all contain a weak peroxisome targeting signal of ty...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617714/ https://www.ncbi.nlm.nih.gov/pubmed/26484888 http://dx.doi.org/10.1371/journal.pone.0140685 |