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Peroxisomal Import Reduces the Proapoptotic Activity of Deubiquitinating Enzyme USP2

The human deubiquitinating enzyme ubiquitin-specific protease 2 (USP2) regulates multiple cellular pathways, including cell proliferation and apoptosis. As a result of alternative splicing four USP2 isoenzymes are expressed in human cells of which all contain a weak peroxisome targeting signal of ty...

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Detalles Bibliográficos
Autores principales: Reglinski, Katharina, Keil, Marina, Altendorf, Sabrina, Waithe, Dominic, Eggeling, Christian, Schliebs, Wolfgang, Erdmann, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617714/
https://www.ncbi.nlm.nih.gov/pubmed/26484888
http://dx.doi.org/10.1371/journal.pone.0140685