Cables1 controls p21/Cip1 protein stability by antagonizing proteasome subunit alpha type 3

The cyclin-dependent kinase inhibitor 1A (CDKN1A), p21/Cip1, is a vital cell cycle regulator, dysregulation of which has been associated with a large number of human malignancies. One critical mechanism that controls p21 function is through its degradation, which allows the activation of its associa...

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Detalles Bibliográficos
Autores principales: Shi, Zhi, Li, Zenggang, Li, Zijian, Cheng, Kejun, Du, Yuhong, Fu, Haian, Khuri, Fadlo R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617825/
https://www.ncbi.nlm.nih.gov/pubmed/24975575
http://dx.doi.org/10.1038/onc.2014.171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617825/
https://www.ncbi.nlm.nih.gov/pubmed/24975575
http://dx.doi.org/10.1038/onc.2014.171

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