Cargando…
Cables1 controls p21/Cip1 protein stability by antagonizing proteasome subunit alpha type 3
The cyclin-dependent kinase inhibitor 1A (CDKN1A), p21/Cip1, is a vital cell cycle regulator, dysregulation of which has been associated with a large number of human malignancies. One critical mechanism that controls p21 function is through its degradation, which allows the activation of its associa...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617825/ https://www.ncbi.nlm.nih.gov/pubmed/24975575 http://dx.doi.org/10.1038/onc.2014.171 |