GC skew defines distinct RNA polymerase pause sites in CpG island promoters

CpG islands (CGIs) are associated with over half of human gene promoters and are characterized by a unique chromatin environment and high levels of bidirectional transcriptional activity relative to surrounding genomic regions, suggesting that RNA polymerase (Pol II) progression past the CGI boundar...

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Detalles Bibliográficos
Autores principales: Kellner, Wendy A., Bell, Joshua S.K., Vertino, Paula M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617957/
https://www.ncbi.nlm.nih.gov/pubmed/26275623
http://dx.doi.org/10.1101/gr.189068.114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617957/
https://www.ncbi.nlm.nih.gov/pubmed/26275623
http://dx.doi.org/10.1101/gr.189068.114

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