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Cooperative target mRNA destabilization and translation inhibition by miR-58 microRNA family in C. elegans

In animals, microRNAs frequently form families with related sequences. The functional relevance of miRNA families and the relative contribution of family members to target repression have remained, however, largely unexplored. Here, we used the Caenorhabditis elegans miR-58 miRNA family, composed pr...

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Detalles Bibliográficos
Autores principales: Subasic, Deni, Brümmer, Anneke, Wu, Yibo, Pinto, Sérgio Morgado, Imig, Jochen, Keller, Martin, Jovanovic, Marko, Lightfoot, Helen Louise, Nasso, Sara, Goetze, Sandra, Brunner, Erich, Hall, Jonathan, Aebersold, Ruedi, Zavolan, Mihaela, Hengartner, Michael O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617964/
https://www.ncbi.nlm.nih.gov/pubmed/26232411
http://dx.doi.org/10.1101/gr.183160.114