Zelda overcomes the high intrinsic nucleosome barrier at enhancers during Drosophila zygotic genome activation

The Drosophila genome activator Vielfaltig (Vfl), also known as Zelda (Zld), is thought to prime enhancers for activation by patterning transcription factors (TFs). Such priming is accompanied by increased chromatin accessibility, but the mechanisms by which this occurs are poorly understood. Here,...

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Detalles Bibliográficos
Autores principales: Sun, Yujia, Nien, Chung-Yi, Chen, Kai, Liu, Hsiao-Yun, Johnston, Jeff, Zeitlinger, Julia, Rushlow, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617966/
https://www.ncbi.nlm.nih.gov/pubmed/26335633
http://dx.doi.org/10.1101/gr.192542.115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617966/
https://www.ncbi.nlm.nih.gov/pubmed/26335633
http://dx.doi.org/10.1101/gr.192542.115

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