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Zelda is differentially required for chromatin accessibility, transcription factor binding, and gene expression in the early Drosophila embryo

The transition from a specified germ cell to a population of pluripotent cells occurs rapidly following fertilization. During this developmental transition, the zygotic genome is largely transcriptionally quiescent and undergoes significant chromatin remodeling. In Drosophila, the DNA-binding protei...

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Detalles Bibliográficos
Autores principales: Schulz, Katharine N., Bondra, Eliana R., Moshe, Arbel, Villalta, Jacqueline E., Lieb, Jason D., Kaplan, Tommy, McKay, Daniel J., Harrison, Melissa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617967/
https://www.ncbi.nlm.nih.gov/pubmed/26335634
http://dx.doi.org/10.1101/gr.192682.115