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Extensive de novo mutation rate variation between individuals and across the genome of Chlamydomonas reinhardtii

Describing the process of spontaneous mutation is fundamental for understanding the genetic basis of disease, the threat posed by declining population size in conservation biology, and much of evolutionary biology. Directly studying spontaneous mutation has been difficult, however, because new mutat...

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Detalles Bibliográficos
Autores principales: Ness, Rob W., Morgan, Andrew D., Vasanthakrishnan, Radhakrishnan B., Colegrave, Nick, Keightley, Peter D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617969/
https://www.ncbi.nlm.nih.gov/pubmed/26260971
http://dx.doi.org/10.1101/gr.191494.115