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Extensive de novo mutation rate variation between individuals and across the genome of Chlamydomonas reinhardtii
Describing the process of spontaneous mutation is fundamental for understanding the genetic basis of disease, the threat posed by declining population size in conservation biology, and much of evolutionary biology. Directly studying spontaneous mutation has been difficult, however, because new mutat...
Autores principales: | Ness, Rob W., Morgan, Andrew D., Vasanthakrishnan, Radhakrishnan B., Colegrave, Nick, Keightley, Peter D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617969/ https://www.ncbi.nlm.nih.gov/pubmed/26260971 http://dx.doi.org/10.1101/gr.191494.115 |
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