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Combinatorial control of Drosophila circular RNA expression by intronic repeats, hnRNPs, and SR proteins

Thousands of eukaryotic protein-coding genes are noncanonically spliced to produce circular RNAs. Bioinformatics has indicated that long introns generally flank exons that circularize in Drosophila, but the underlying mechanisms by which these circular RNAs are generated are largely unknown. Here, u...

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Detalles Bibliográficos
Autores principales: Kramer, Marianne C., Liang, Dongming, Tatomer, Deirdre C., Gold, Beth, March, Zachary M., Cherry, Sara, Wilusz, Jeremy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617980/
https://www.ncbi.nlm.nih.gov/pubmed/26450910
http://dx.doi.org/10.1101/gad.270421.115