TIMELESS Forms a Complex with PARP1 Distinct from Its Complex with TIPIN and Plays a Role in the DNA Damage Response

PARP1 is the main sensor of single- and double-strand breaks in DNA and, in building chains of poly(ADP-ribose), promotes the recruitment of many downstream signaling and effector proteins involved in the DNA damage response (DDR). We show a robust physical interaction between PARP1 and the replicat...

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Detalles Bibliográficos
Autores principales: Young, Lauren M., Marzio, Antonio, Perez-Duran, Pablo, Reid, Dylan A., Meredith, Daniel N., Roberti, Domenico, Star, Ayelet, Rothenberg, Eli, Ueberheide, Beatrix, Pagano, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618055/
https://www.ncbi.nlm.nih.gov/pubmed/26456830
http://dx.doi.org/10.1016/j.celrep.2015.09.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618055/
https://www.ncbi.nlm.nih.gov/pubmed/26456830
http://dx.doi.org/10.1016/j.celrep.2015.09.017

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