Control of peripheral tolerance by regulatory T cell-intrinsic Notch signaling

Notch receptors direct the differentiation of T helper (T(H)) cell subsets, but their influence on regulatory T (T(reg)) cell responses is obscure. We here report that lineage-specific deletion of components of the Notch pathway enhanced T(reg) cell-mediated suppression of T(H)1 responses, and prote...

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Detalles Bibliográficos
Autores principales: Charbonnier, Louis-Marie, Wang, Sen, Georgiev, Peter, Sefik, Esen, Chatila, Talal A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618075/
https://www.ncbi.nlm.nih.gov/pubmed/26437242
http://dx.doi.org/10.1038/ni.3288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618075/
https://www.ncbi.nlm.nih.gov/pubmed/26437242
http://dx.doi.org/10.1038/ni.3288

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