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Plasmodium parasites mount an arrest response to dihydroartemisinin, as revealed by whole transcriptome shotgun sequencing (RNA-seq) and microarray study

BACKGROUND: Control of malaria is threatened by emerging parasite resistance to artemisinin and derivative drug (ART) therapies. The molecular detail of how Plasmodium malaria parasites respond to ART and how this could contribute to resistance are not well understood. To address this question, we p...

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Detalles Bibliográficos
Autores principales: Shaw, Philip J., Chaotheing, Sastra, Kaewprommal, Pavita, Piriyapongsa, Jittima, Wongsombat, Chayaphat, Suwannakitti, Nattida, Koonyosying, Pongpisid, Uthaipibull, Chairat, Yuthavong, Yongyuth, Kamchonwongpaisan, Sumalee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618149/
https://www.ncbi.nlm.nih.gov/pubmed/26490244
http://dx.doi.org/10.1186/s12864-015-2040-0