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High-dimensional immune profiling of total and rotavirus VP6-specific intestinal and circulating B cells by mass cytometry

In-depth phenotyping of human intestinal antibody secreting cells (ASCs) and their precursors is important for developing improved mucosal vaccines. We used single-cell mass cytometry to simultaneously analyze 34 differentiation and trafficking markers on intestinal and circulating B cells. In addit...

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Detalles Bibliográficos
Autores principales: Nair, Nitya, Newell, Evan W., Vollmers, Christopher, Quake, Stephen R., Morton, John M., Davis, Mark M., He, Xiao-Song, Greenberg, Harry B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618273/
https://www.ncbi.nlm.nih.gov/pubmed/25899688
http://dx.doi.org/10.1038/mi.2015.36