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SIRT1 protects against myocardial ischemia–reperfusion injury via activating eNOS in diabetic rats
BACKGROUND: Diabetic patients are more sensitive to myocardial ischemic injury than non-diabetic patients. Silent information regulator 1 (SIRT1) is a nicotinamide adenine dinucleotide-dependent histone deacetylase making the heart more resistant to ischemic injury. As SIRT1 expression is considered...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618275/ https://www.ncbi.nlm.nih.gov/pubmed/26489513 http://dx.doi.org/10.1186/s12933-015-0299-8 |