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Evaluation of BRCA1-related molecular features and microRNAs as prognostic factors for triple negative breast cancers
BACKGROUND: The BRCA1 gene plays a key role in triple negative breast cancers (TNBCs), in which its expression can be lost by multiple mechanisms: germinal mutation followed by deletion of the second allele; negative regulation by promoter methylation; or miRNA-mediated silencing. This study aimed t...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618357/ https://www.ncbi.nlm.nih.gov/pubmed/26490435 http://dx.doi.org/10.1186/s12885-015-1740-9 |