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Ifosfamide-loaded poly (lactic-co-glycolic acid) PLGA-dextran polymeric nanoparticles to improve the antitumor efficacy in Osteosarcoma

BACKGROUND: Osteosarcoma is a typical bone cancer that primarily affects adolescents. The therapeutic activity of drugs is limited by their severe drug-related toxicities, therefore, a therapeutic approach which is less toxic and highly effective in tumor is of utmost importance. METHOD: In this stu...

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Detalles Bibliográficos
Autores principales: Chen, Bin, Yang, Jie-Zuan, Wang, Li-Feng, Zhang, Yi-Jun, Lin, Xiang-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618398/
https://www.ncbi.nlm.nih.gov/pubmed/26486165
http://dx.doi.org/10.1186/s12885-015-1735-6