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New Insights into Orphan Nuclear Receptor SHP in Liver Cancer

Small heterodimer partner (SHP; NR0B2) is a unique orphan nuclear receptor (NR) that contains a putative ligand-binding domain but lacks a DNA-binding domain. SHP is a transcriptional corepressor affecting diverse metabolic processes including bile acid synthesis, cholesterol and lipid metabolism, g...

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Detalles Bibliográficos
Autores principales: Zou, An, Lehn, Sarah, Magee, Nancy, Zhang, Yuxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618403/
https://www.ncbi.nlm.nih.gov/pubmed/26504773
http://dx.doi.org/10.11131/2015/101162