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Analysis of Erythrocyte Glycophorin-A Variants by Flow Cytometry in Lung Disease Patients Detects the Effect of Tobacco Smoke

The glycophoryn A (GPA) assay evaluates somatic in vivo mutations. It is considered a cumulative biodosimeter for genotoxic exposures and is under evaluation in cancer risk assessment. GPA, a polymorphic membrane protein of the erythrocytes, determines the MN blood groups. The N0 and NN variant freq...

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Detalles Bibliográficos
Autores principales: Neri, Monica, Geido, Elio, Filiberti, Rosangela, Orecchia, Roberto, Di Vinci, Angela, Cafferata, Mara, Tassara, Elisabetta, Puntoni, Riccardo, Giaretti, Walter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618435/
https://www.ncbi.nlm.nih.gov/pubmed/11254223
http://dx.doi.org/10.1155/2000/512786