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Differential Notch and TGFβ Signaling in Primary Colorectal Tumors and Their Corresponding Metastases

Background: Loss of epithelial morphology and the acquisition of mesenchymal characteristics may contribute to metastasis formation during colorectal tumorigenesis. The Wnt, Notch and TGFβ signaling pathways control tissue homeostasis and tumor development in the gut. The relationship between the ac...

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Detalles Bibliográficos
Autores principales: Veenendaal, Liesbeth M., Kranenburg, Onno, Smakman, Niels, Klomp, Annemarie, Borel Rinkes, Inne H. M., van Diest, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618437/
https://www.ncbi.nlm.nih.gov/pubmed/18219106
http://dx.doi.org/10.1155/2008/839076