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RANK Signaling Amplifies WNT-Responsive Mammary Progenitors through R-SPONDIN1
Systemic and local signals must be integrated by mammary stem and progenitor cells to regulate their cyclic growth and turnover in the adult gland. Here, we show RANK-positive luminal progenitors exhibiting WNT pathway activation are selectively expanded in the human breast during the progesterone-h...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618445/ https://www.ncbi.nlm.nih.gov/pubmed/26095608 http://dx.doi.org/10.1016/j.stemcr.2015.05.012 |