RANK Signaling Amplifies WNT-Responsive Mammary Progenitors through R-SPONDIN1

Systemic and local signals must be integrated by mammary stem and progenitor cells to regulate their cyclic growth and turnover in the adult gland. Here, we show RANK-positive luminal progenitors exhibiting WNT pathway activation are selectively expanded in the human breast during the progesterone-h...

Descripción completa

Detalles Bibliográficos
Autores principales: Joshi, Purna A., Waterhouse, Paul D., Kannan, Nagarajan, Narala, Swami, Fang, Hui, Di Grappa, Marco A., Jackson, Hartland W., Penninger, Josef M., Eaves, Connie, Khokha, Rama
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618445/
https://www.ncbi.nlm.nih.gov/pubmed/26095608
http://dx.doi.org/10.1016/j.stemcr.2015.05.012

Ejemplares similares

Ejemplares similares