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ANXA3/JNK Signaling Promotes Self-Renewal and Tumor Growth, and Its Blockade Provides a Therapeutic Target for Hepatocellular Carcinoma

Frequent tumor relapse in hepatocellular carcinoma (HCC) has been commonly attributed to the presence of residual cancer stem cells (CSCs) after conventional treatments. We have previously identified and characterized CD133 to mark a specific CSC subset in HCC. In the present study, we found endogen...

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Detalles Bibliográficos
Autores principales: Tong, Man, Fung, Tsun-Ming, Luk, Steve T., Ng, Kai-Yu, Lee, Terence K., Lin, Chi-Ho, Yam, Judy W., Chan, Kwok Wah, Ng, Fai, Zheng, Bo-Jian, Yuan, Yun-Fei, Xie, Dan, Lo, Chung-Mau, Man, Kwan, Guan, Xin-Yuan, Ma, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618447/
https://www.ncbi.nlm.nih.gov/pubmed/26095609
http://dx.doi.org/10.1016/j.stemcr.2015.05.013