Distinct Neurodegenerative Changes in an Induced Pluripotent Stem Cell Model of Frontotemporal Dementia Linked to Mutant TAU Protein

Frontotemporal dementia (FTD) is a frequent form of early-onset dementia and can be caused by mutations in MAPT encoding the microtubule-associated protein TAU. Because of limited availability of neural cells from patients’ brains, the underlying mechanisms of neurodegeneration in FTD are poorly und...

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Detalles Bibliográficos
Autores principales: Ehrlich, Marc, Hallmann, Anna-Lena, Reinhardt, Peter, Araúzo-Bravo, Marcos J., Korr, Sabrina, Röpke, Albrecht, Psathaki, Olympia E., Ehling, Petra, Meuth, Sven G., Oblak, Adrian L., Murrell, Jill R., Ghetti, Bernardino, Zaehres, Holm, Schöler, Hans R., Sterneckert, Jared, Kuhlmann, Tanja, Hargus, Gunnar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618448/
https://www.ncbi.nlm.nih.gov/pubmed/26143746
http://dx.doi.org/10.1016/j.stemcr.2015.06.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618448/
https://www.ncbi.nlm.nih.gov/pubmed/26143746
http://dx.doi.org/10.1016/j.stemcr.2015.06.001

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